Biologie Des Télomères - Fontenay-aux-Roses, France - Université Paris-Saclay GSLife Sciences and Health

Sophie Dupont

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Sophie Dupont

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Description

Biologie des télomères // Telomere biology:

  • Réf
-
ABG-112218

ADUM-47827

  • Sujet de Thèse 18/03/2023
  • Financement public/privé
  • Université Paris-Saclay GSLife Sciences and Health
  • Lieu de travail
  • FontenayauxRoses cedex
  • France
  • Intitulé du sujet
  • Biologie des télomères // Telomere biology
  • Mots clés télomère, chromosome, ADN, replication, cancer, vieillissement
- telomere, chromosome, DNA, replication, cancer, aging
Description du sujet:

  • We are a team seeking to understand the mechanisms that underpin telomere stability and how this intersects with DNA repair, DNA replication, chromosome organisation and chromosome segregation.

  • Projects that can be pursued will address the molecular basis of telomere end protection, telomere replication, telomere length homeostasis, telomere recombination and/or telomere segregation during mitosis.
  • To achieve these aims, a large body of methods and tools will be used and developed, combining molecular genetics, live microscopy, biochemistry, structure and modelling.

We are a team seeking to understand the mechanisms that underpin telomere stability and how this intersects with DNA repair, DNA replication, chromosome organisation and chromosome segregation.


  • Projects that can be pursued will address the molecular basis of telomere end protection, telomere replication, telomere length homeostasis, telomere recombination and/or telomere segregation during mitosis.
  • To achieve these aims, a large body of methods and tools will be used and developed, combining molecular genetics, live microscopy, biochemistry, structure and modelling.

Début de la thèse : 01/10/2023
Nature du financement:


  • Financement public/privé
    Précisions sur le financement:


  • Financement du CEA

  • CFR (Contrat formation par la recherche)
    Présentation établissement et labo d'accueil:
  • Université Paris-Saclay GSLife Sciences and Health
    Etablissement délivrant le doctorat:
  • Université Paris-Saclay GSLife Sciences and Health

Ecole doctorale:

  • 577 Structure et Dynamique des Systèmes Vivants
  • M2 biologie ou biophysique
  • M2 in biologie or biophysics 14/05/2023

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