PhD : Genetics of mortality outbreaks in Mytilus sp. (M/F) (BB-E7B50)
Trouvé dans: Jooble FR
The Institute and the recruiting departement
A pioneer in ocean science, IFREMER’s cutting-edge research is grounded in sustainable development and open science. Our vision is to advance science, expertise and innovation to:
Protect and restore the ocean
Sustainably use marine resources to benefit society
Create and share ocean data, information & knowledge.
With more than 1,500 personnel spread along the French coastline in more than 20 sites, the Institute explores the 3 great oceans: the Indian, Atlantic and Pacific oceans. A leader in ocean science, IFREMER is managing the French Oceanographic Fleet and its dedicated scientists create ground-breaking technology to push the boundaries of ocean exploration and knowledge, from the abyss to the atmosphere-ocean interface.
Well-established in the international scientific community, our scientists, engineers and technicians are committed to advance knowledge about our planet’s last unexplored frontiers. They provide the science we need for informed decision-making and public policy and they transfer this knowledge and technology to businesses to fulfill public and private needs. Core to our mission is also to strengthen public awareness about the importance of understanding the ocean and its resources, and empowering future generations of leaders through education and outreach national campaigns.
Founded in 1984, IFREMER is a French public organization and its budget approximates 240 million euros. It is operating under the joint authority of the French Ministry for Higher Education, Research and Innovation, the French Ministry for the Ecological and Solidary Transition, and the French Ministry of Agriculture and Food.
General areas of responsibility
Located in La Tremblade, the Laboratory of Genetics and Pathology of Marine Molluscs (LGPMM) specializes in genetic approaches targeting genomes, domestication and genetic improvement of bivalves, and the study of diseases affecting marine molluscs. In addition to its own infrastructures and equipment, one of the major assets of the LGPMM concerns the Ifremer facilities in La Tremblade, particularly within the marine molluscs platform (PMM) to produce and test the experimental batches of molluscs. The LGPMM maintains numerous collaborations with national and international teams, through its current involvement in the ANR Decicomp, H2020 NewTechAqua or EATFISH projects, H2020-MSCA-ITN-2020 project, in which the thesis described below is part of.
EATFISH is a European project involving 13 partners, including Ifremer, aimed at training researchers for the benefit of aquaculture. Ifremer will host a doctoral student who will complete 6 to 8 months of secondment attachement in several project partners. Ifremer is participating in the WP2, dedicated to aquaculture, focusing on food, genetics, diseases and production systems. The subject of the thesis proposed by Ifremer within EATFISH addresses the genetic determinism of mortality in blue mussels.
French mussel farming is based on the cultivation of two species M. edulis and M. galloprovincialis, as well as their hybrids, naturally present on all French coasts: Mediterranean, Atlantic and English Channel. Since 2014, significant mortalities have affected the mussel aquaculture industry from Charente-Maritime, Vendée, Loire Atlantique, to the Haut de France region closed to Belgium.
The first results showed that both species and their hybrids were affected by the episodes of mortality, with high mortalities for M. edulis, intermediate for hybrid mussels and lower for M. galloprovincialis. A first generation of mass selection also made it possible to halve the mortalities in M. edulis, making it possible to offer solutions to the mussel industry to reduce the mortalities and therefore reduce the economic impact of the losses suffered. The cause of the deaths remains to be clarified to this day, and tests combining field approaches / experimental infections will be essential to rule out or confirm the role of pathogens. At the same time, the inter-individual variation in cytogenetic quality observed in mussels in relation to the establishment and progression of a neoplasic process has also been shown to be a major factor in the phenomenon of abnormal mortalities.
The thesis aims to study the genetic determinisms of abnormal mortalities of blue mussels. The objectives are:
- determine the genetic parameters (heritability and genetic correlations) of mussel mortalities in the two species of mussels, and their hybrids,
- produce a new generation of mass selection and calculate the response to selection for the character of cytogenetic quality,
- produce families of M. edulis, M. galloprovincialis and hybrids with contrasting resistance levels, and test their progenies in production sites
Blue mussels, genetic, selection, cytogenetic quality,
How to apply for this position ?
Your application file must include :
- a curriculum vitae
- a covering letter
- a reference letter
- an academic transcript (Bachelor + Master 1 and first semester Master 2)
Your application must be compiled into 2 PDF files, up to 1.5 MB for each file:
In case of any problem in attaching your documents, please upload your CV on this page (this step is mandatory for your application to be considered) and send all the documents to the thesis supervisor : .
The deadline for applications is 2nd of May, 2021. Nevertheless, we strongly urge you to let us know as soon as possible of your intention to apply, by contacting the subject supervisor.
Doctoral students' contracts will start as of October 1st, 2021, subject to the submission of administrative documents authorizing Ifremer to recruit the doctoral student (certificate of completion of the Master 2 or engineering degree + visa for foreign doctoral students outside the EU).Offer Requirements
Required Knowledge, skills, and characteristics
- Master 2 in genetics, more specifically in quantitative genetics. Relational quality. Fluent in English (mandatory) and French (optional).
- The candidate must not have resided or carried out his main activity (work, studies, etc.) in France for more than 12 months during the last three years.
Specific working conditions
- Secondment attachment for 6 to 8 months during the thesis with partners of the EATFISH project, in particular NOFIMA (Norway) to follow a training course on genomic markers of resistance to diseases in fish, sysaaf (France) for exploitation genomic markers.
- Work in the laboratory (flow cytometry, molecular biology), hatchery and mussel farms,
Phd is a real opportunity to work on Ifremer's scientific and technological priority themes.
calendar_todayil y a 5 jours
location_on La Tremblade, France
work IFREMER - Institut Français de Recherche pour l'Exploitation de la MER