Rechercheur expérimental spécialisé en interactions RNA-proteine - Strasbourg - beBeeFlavivirus

Intitulé du poste: doctorant (h/f) pour l'identification et la caractérisation de complexes ribonucléoprotéiques i

Description

Poste de recherche

Identifiez les complexes ribonucléoprotéiques clés pour la réplication des virus de la Dengue et du Zika

Dans le cadre d'un projet international, nous recherchons un doctorant (H/F) qui identifie et caractérise les facteurs chez le moustique interagissant avec l'ARN génomique des Flavivirus. Vous serez chargé(e) d'étudier au niveau structural et biophysique plusieurs complexes ribonucléoprotéiques impliquant des régions non codantes du génome viral.

Nos objectifs scientifiques

• Identifier les protéines hôtes pertinentes pour la réplication virale.


• Caractériser structuralement et biophysiquement les complexes ARN-protée affectant directement ce cycle vital.

Pour atteindre ces buts vous utiliserez une approche multi-disciplinaire combinant expertise en virologie molécullaire (Cryo-Microscopie Electronique , Réseance Magnétique Nuclèaire_ , etc.)
et collaboration internationale incluant partenaires brésiliens.
L'objectif premier est de comprendre à nouveaux composes intervenants dans processus virulent nécessitant antiviraux futurs razonnels !

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