As a member of the Microbial Engineering team within the Bioengineering Center of Excellence (Lesaffre Institute for Science and Technology) in France, your role and responsibilitites will BE :
BE the point of reference and subject-matter expert for all the Lesaffre's group classical breeding programs for improvement of fungi, yeast and bacteria, with classical breeding including, for instance, adaptive laboratory evolution (ALE), mutagenesis, cell fusion, hybridization/crossing, marker-assisted selection, genome-wide association studies, natural transformation, transduction, conjugation. Main assignments will focus on quantitative yeast genetics, with fungal and bacterial genetics as secondary assignment, but still mission-critical, responsibilities in the long term.
Study, design, develop and exploit microbial genetic diversity by collaboratively using a combination of highthroughput system biology (phenomics, genomics, transcriptomics, proteomics, metabolomics) data, statistics, automated ALE, innovative breeding technology and leveraging biofoundry approaches.
Lead genotypes selection and strain improvement programs focusing on predictive modeling for optimal selection of parents, progeny and hybrids for applications for instance in breadmaking, winemaking, ethanol, cell extracts and feeds.
Combine biological experiments data and theory, simulations, and data analysis to design optimized microbial strains improvement schemes (breeding, evolution, and/or mutagenesis) and manage its execution by operations support teams.
Independently troubleshoot technically complex problems and propose solutions or experimental plans to resolve or correct for them.
Maintain highquality documentation of your work and discoveries, in the forms of written reports, technical presentations, electronic lab notebooks, internal database records, and software documentation.
Assignments can BE subject to review and changes based on company priorities.
