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Immuno-Oncology in vivo Study Manager - Bordeaux, France - Explicyte
Description
Immuno-Oncology in vivo Study Manager
Job offer #:SM0424
Type: Full time position, permanent contract
Location: Bordeaux, France
Explicyte is an Immuno-Oncology focused Contract Research Organization. We offer high-level scientific research expertise and comprehensive service platforms ranging from in vitro to translational applications, together with in vivo models, to support our Partners' research programs.
The position
To strengthen our in vivo preclinical activities, we are looking for an experienced in vivo Immuno-Oncology Study Manager, diligent, motivated and ready to take up with us the implementation of projects and their protocols, relevant for the testing and development of novel immunotherapeutic modalities.
In your role, you will be accountable for the technical and organizational management of Sponsors' and R&D in vivo studies, from their implementation and performance to data analysis. You will timeously provide deliverables with respect to the project's requirements and timelines.
You will closely interact with the in vivo team members. You will report to the Study Directors and CSO.
Your skills & traits
• Ph.D - or equivalent - in science and health-related fields
• Accreditation in animal experimentation level 1/2 is mandatory, ethical standards and regulations
• Deep knowledge and mastery of preclinical tumor-bearing mouse models
• Expertise in tissue collection and processing for flow cytometry-based analysis
• Knowledge in the fields of tumor immunology and cancer therapies
• Minimum 1-2 years' experience in in vivo preclinical development in a health industry: Pharma, Biotech, CRO...
• Project management experience (from planning to closing projects)
• Excellent diligence
• Strong interpersonal & organizational skills
• Ability to easily adapt to changing priorities and challenges
• Enthusiasm, high motivation, and integrity
Your missions & responsibilities
• Provide draft protocols according to the proposed scientific and experimental strategies
• Implement studies - relying on undeniable organizational skills - according to their design and established schedules
• Manage and perform - diligently - in vivo and ex vivo experiments
• Tumor cell line culture and maintenance
• Mastery of anesthesia and surgical gestures
• Tumor cell inoculation (subcutaneous, intradermic, intracranial, mammary fat pad, intrasplenic, etc.)
• In vivo monitoring: tumor growth (physical, bioluminescence), body weight and survival, tolerability evaluation
• Mastery of Neuro-oncology related in vivo protocols and models is a plus
• Treatment administration (oral, intraperitoneal, intravenous, intratumoral)
• Sampling of biological tissues (blood, tumor, lymph nodes, organs)
• Ex vivo processing of collected samples for immune or tumor cell isolation, or for further analyses (FACS, ELISA...)
• Achieve accurate and timely acquisition of in vivo monitoring measures
• Timely capture, analyze and compile data, including quality controls
• Ensure accuracy and completeness of study documentation and timely provide study deliverables
• Write and submit animal referrals for ethical committee approval
• Write internal protocols and standard operating procedures
We offer more than a job
You are passionate about science and preclinical animal research for the purpose of developing new medicines for cancer patients, and, above all, you demonstrate innately rooted skills of organization and diligence?
Join a dynamic and growing company while benefiting from all the support you need to succeed in your work
Submit your resume and cover letter
