Investigating Periodontitis with X-ray - Lyon, France - Université Grenoble Alpes
Description
Investigating periodontitis with X-ray Modulation-Based Imaging (MOBI):
- Réf
ABG-123254 - Sujet de Thèse 22/04/2024
- Financement public/privé
- Université Grenoble Alpes
- Lieu de travail
- Lyon
- Auvergne-RhôneAlpes
- France
- Intitulé du sujet
- Investigating periodontitis with Xray Modulation-Based Imaging (MOBI)
- Champs scientifiques
- Numérique
- Physique
Description du sujet:
- The aim of the PhD thesis is to develop image analysis frameworks for investigating periodontal tissues with MOBI. Specifically, we aim to analyze hard and soft periodontal tissues in _ex vivo_ human samples and in mouse models of periodontitis. We further aim to detect nanoparticles that will be used for functional imaging (microvascularization) and for cellular imaging (stem cells as innovative therapy for periodontitis). Because MOBI imaging technique is totally new and because there exists no other imaging technique allowing the diagnosis and monitoring of periodontitis, one of the challenges will be to decipher the imaging semiology of the MOBI images, in collaboration with the dentists involved in the project.
- This is an interdisciplinary collaborative project that involves 4 labs located in Paris (BRIO), Lyon (CarMeN), Grenoble (Strobe) and Toulouse (Restore). It is expected to have a high clinical impact, as periodontitis is a major public health issue.
Practical information:The student will be based in the Carmen lab in Lyon. Short missions in Grenoble and Toulouse will occur quarterly. The net income is approx.
1700 eur/month
PhD supervisors:
- Marlène Wiart, PhD
- Directrice de recherche CNRS
- CarMeN lab, Lyon
- Emmanuel Brun, PhD
- Directeur de recherche Inserm
- Strobe lab, Grenoble
- Paul Monsarrat/Philippe Kémoun, PhD
- PU-PH Médecine Orale
- RESTORE lab, Toulouse
Prise de fonction: - 01/10/2024
Nature du financement: - Financement public/privé
Précisions sur le financement:
- ANR
Présentation établissement et labo d'accueil:
- Université Grenoble Alpes
- This is an interdisciplinary collaborative project that involves 4 labs located in Paris (BRIO), Lyon (CarMeN), Grenoble (Strobe) and Toulouse (Restore). It is expected to have a high clinical impact, as periodontitis is a major public health issue. 31/05/2024
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