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    Research engineer - Paris, France - Université PSL

    Université PSL
    Université PSL Paris, France

    il y a 3 semaines

    Default job background
    À temps plein
    Description

    About us

    The Curie Institute Research Center

    The "Institut Curie" is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness.

    The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

    Mission

    Laboratory

    The researcher will join the Innate Immunity in Physiology and Cancer team (https://institut-), within the Immunology and Cancer Unit (U932). The team specialises in studying the molecular mechanisms of defence in place to protect cells from insults, including from pathogen infection. Mechanisms are explored in non-transformed cells, as well as in cancer. In the latter, we specifically assess if mechanisms of interest can be targeted for antitumor therapy. The team recently discovered a novel inflammatory protein which plays a pivotal role in the toll-like receptor pathway of innate immunity, by producing an inflammatory second messenger. Our goal is now to determine if the inflammatory properties of this protein could be harnessed to engineer novel immunotherapies against cancer.

    Missions

    The hired researcher will pilot a project dedicated to transform the newly-discovered protein into an immunotherapy active against cancer. It entails:

    Cellular and molecular biology, including cell culture, nucleic acid and protein analysis

    Experimentation with mouse models of tumors

    Data analysis, discussion and presentation in team meetings

    Team work

    Bibliography

    Profile

    Candidate Profile

    Training and experience required

    Open to Masters as well as PhDs

    Professional experience will be considered favourably

    Licence for animal experimentation will be considered favourably

    Experimental techniques in cellular and molecular biology (nucleic acid and protein manipulation, cell culture)

    Skills required

    English

    Independance

    Aptitutde for team work is pivotal

    All our opportunities are open to people with disabilities

    Contract information

    Type of contract: CDD

    Starting date: July 2024

    Duration: 18 months

    Working time: full time

    Remuneration: according to the current grids

    Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

    Location of the position: Paris

    Reference: NA

    Please send your CV, letter of motivation and 2 references

    Publication date: 13/05/2024

    Deadline for application: 13/06/24

    Institut Curie is an inclusive, equal opportunity employer

    and is dedicated to the highest standards of research integrity.

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